Spinal
Cord Injury
By
Alyssa Flake and Kari Durrant
Winter
2013
RECM
470
Table of Contents
- Spinal Cord and Column
- Facts and Statistics
- Levels and Classification of Injury
- Functional Goals
- TR Implications
- Adaptive Technologies
- Resources
- Associations and Organizations
- Glossary
Spinal
Cord & Column Information
The
spinal column, more commonly called the backbone, is made up
primarily of vertebrae, discs, and the spinal cord. Acting as a
communication conduit for the brain, signals are transmitted and
received through the spinal cord.
When
an injury to the spinal cord occurs the flow of information from that
point down is stopped. This break in instructions to the arms, legs,
and other parts of the body will prevent the individual from moving,
sometimes breathing, and obstructs or stops any sense of feeling or
touch.
Spinal
Cord & Column
The
spinal column is separated into 5 specific functional areas.
- Cervical / C 1-7
- Thoracic / T 1 - 12
- Lumbar / L 1 - 5
- Sacral
- Coccyx
The spinal cord is a bundle of nerve cells and fibers wrapped together extending down from the brain stem to the lower back. The cord is protected by a kind of bone tunnel made up of vertebrae which are separated by membranes called discs. The brain sends electrical signals through the spinal cord, giving instructions to the legs, arms, and other areas of the body.
Vertebrae
There
are 33 vertebrae that make up the bone structure of the spinal
column, with the last four being fused together to make the tailbone.
Discs
Each
vertebrae is separated by a soft bone substance, called a disc, which
acts as a cushion and a seal at the same time.
Complete
& Incomplete SCI
An SCI is categorized as either "complete" or "incomplete". A "complete" SCI means a total loss of function and sensation below the affected vertebrae, and an "incomplete" SCI means only partial loss of function or
An SCI is categorized as either "complete" or "incomplete". A "complete" SCI means a total loss of function and sensation below the affected vertebrae, and an "incomplete" SCI means only partial loss of function or
sensation.
Cervical
Spine
There
are seven cervical bones or vertebrae. The cervical bones are
designed to allow flexion, extension, bending, and turning of the
head. They are smaller than the other vertebrae, which allows a
greater amount of movement.
Each
cervical vertebra consists of two parts, a body and a protective arch
for the spinal cord called the neural arch. Fractures or injuries can
occur to the body, lim pedicles, or processes. Each vertebra
articulates with the one above it and the one below it.
Thoracic
Spine
In
the chest region the thoracic spine attaches to the ribs. There are
12 vertebrae in the thoracic region.
The
spinal canal in the thoracic region is relatively smaller than the
cervical or lumbar areas. This makes the thoracic spinal cord at
greater risk if there is a fracture.
The
motion that occurs in the thoracic spine is mostly rotation. The ribs
prevent bending to the side. A small amount of movement occurs in
bending forward and backward.
Lumbosacral
Spine
The
lumbar vertebrae are large, wide, and thick. There are five vertebrae
in the lumbar spine. The lowest lumbar vertebra, L5, articulates with
the sacrum. The sacrum attaches to the pelvis.
The
main motions of the lumbar area are bending forward and extending
backwards. Bending to the side also occurs.
NEUROANATOMY
Just
like the spinal column is divided into cervical, thoracic, and lumbar
regions, so is the spinal cord. Each portion of the spinal cord is
divided into specific neurological segments.
The
cervical spinal cord is divided into eight levels. Each level
contributes to different functions in the neck and the arms.
Sensations from the body are similarly transported from the skin and
other areas of the body from the neck, shoulders, and arms up to the
brain.
In
the thoracic region the nerves of the spinal cord supply muscles of
the chest that help in breathing and coughing. This region also
contains nerves in the sympathetic nervous system.
The
lumbosacral spinal cord and nerve supply legs, pelvis, and bowel and
bladder. Sensations from the feet, legs, pelvis, and lower abdomen
are transmitted through the lumbosacral nerves and spinal cord to
higher segments and eventually the brain.
Nerve
Pathways
There
are many nerve pathways that transmit signals up and down the spinal
cord. Some supply sensation from the skin and outer portions of the
body. Others supply sensation from deeper structures such as the
organs in the belly, the pelvis, or other areas. Other nerves
transmit signals from the brain to the body. Still others work at the
level of the spinal cord and act as "go betweens" in the
signal transmission process.
The
Motor Neuron
The
upper motor neuron refers to injuries that are above the level of the
anterior horn cell. This results in a spastic type of paralysis.
Conversely, the lower motor neuron injury refers to an injury at or
below the anterior horn cell that results in the flaccid type
paralysis. The terms neurogenic bowel and neurogenic bladder are used
to describe abnormal bowel and bladder function and can be classified
as either an upper motor neuron or lower motor neuron type of
problem. In general, those patients with an upper motor neuron
paralysis will have an upper motor neuron bowel and bladder, and
those with lower motor neuron injuries will have a lower motor neuron
picture of the bowel and bladder. Adequate bowel and bladder
management is critical for adequate reintegration of the
patient/client into the community and hopefully into the work place.
Sensory
Pathways
Feelings
from the body such as hot, cold, pain, and touch, are transmitted to
the skin and other parts of the body to the brain where sensations
are "felt". These pathways are called the sensory pathways.
Once
signals enter the spinal cord, they are sent up to the brain.
Different types of sensation are sent in different pathways, called
"tracts". The tracts that carry sensations of pain and
temperature to the brain are in the middle part of the spinal cord.
These tracts are called the "spinothalamic". Other tracts
carry sensation of position and light touch. These nerve impulses are
carried along the back part of the spinal cord in what are called
"dorsal columns" of the spinal cord.
Autonomic
Nerve Pathways
Another
type of special nerves are the autonomic nerves. In spinal cord
injuries, they are very important. The autonomic nerves are divided
into two types: the sympathetic and parasympathetic nerves.
The
autonomic nervous system influences the activities of involuntary
(also known as smooth) muscles, the heart muscle, and glands that
release certain hormones. It controls cardiovascular, digestive, and
respiratory systems. These systems work in a generally "involuntary"
fashion. The primary role of the autonomic nervous system is to
maintain a stable internal environment within the body. The heart and
blood vessels are controlled by the autonomic nervous system. The
sympathetic nerves help to control blood pressure based on the
physical demands placed on the body. It also helps to control heart
rate. The sympathetic nerves, when stimulated, cause the heart to
beat faster.
Sympathetic
Nerves
The
sympathetic nerves also cause constriction of the blood vessels
throughout the body. When this happens, the amount of blood that is
returned to the heart increases. These effects will increase blood
pressure. Other effects include an increase in sweating and increased
irritability or a sensation of anxiety.
When
spinal cord injury is at or above the T6 level the sympathetic nerves
below the injury become disconnected from the nerves above. They
continue to operate automatically once the period of spinal shock is
over. Anything that simulates the sympathetic nerves can cause them
to become overactive. This over-activity of the sympathetic nerves is
what is called autonomic dysreflexia.
Parasympathetic
Nerves
The
parasympathetic nerves act in an opposite manner to the sympathetic
nerves. These nerves tend to dilate blood vessels and slow down the
heart. The most important nerve that carries parasympathetic fibers
is the vagus nerve. This nerve carries parasympathetic signals to the
heart to decrease heart rate. Other nerves supply the blood vessels
to the organs of the abdomen and skin.
The
parasympathetic nerves arise from two areas. The fibers that supply
the organs of the abdomen, heart, lungs, and skin above the waist
begin at the level of the brain and very high spinal cord. The nerves
that supply the reproductive organs, pelvis, and leg begin at the
sacral level, or lowest part of the spinal cord. After a spinal cord
injury, the parasympathetic nerves that begin at the brain continue
to work, even during the phase of spinal shock. When dysreflexia
occurs, the parasympathetic nerves attempt to control rapidly
increasing blood pressure by slowing down the heart.
Spinal
Cord Injury Facts & Statistics
Who
Do Spinal Cord Injuries Affect in the United States?
- 250,000 Americans are spinal cord injured.
- 52% of spinal cord injured individuals are considered paraplegic and 47% quadriplegic.
- Approximately 11,000 new injuries occur each year.
- 82% are male.
- 56% of injuries occur between the ages of 16 and 30.
- The average age of spinal cord injured person is 31.
- SCI injuries are most commonly caused by:
- Vehicular accidents 37%
- Violence 28%
- Falls 21%
- Sports-related 6%
- Other 8%
- The most rapidly increasing cause of injuries is due to violence; vehicular accident injuries are decreasing in number.
- 89% of all SCI individuals are discharged from hospitals to a private home, 4.3% are discharged to nursing homes.
- Only 52% of SCI individuals are covered by private health insurance at time of injury.
What
Do Spinal Cord Injuries Really Cost?
- Length of initial hospitalization following injury in acute care units: 15 days
- Average stay in rehabilitation unit: 44 days
- Initial hospitalization costs following injury: $140,000
- Average first year expenses for a SCI injury (all groups): $198,000
- First year expenses for paraplegics: $152,000
- First year expenses for quadriplegics: $417,000
- Average lifetime costs for paraplegics, age of injury 25: $428,000
- Average lifetime costs for quadriplegics, age of injury 25: $1.35 million
- Percentage of SCI individuals who are covered by private health insurance at time of injury 52% - Compare health insurance atprivatemedicalhealthinsurance.org.uk
- Percentage of SCI individuals unemployed eight years after injury 63%. (Note: unemployment rate when this article was written was 4.7%)
Source:
The University of Alabama National Spinal Cord Injury Statistical
Center - March 2002
Spinal
Cord Injury Statistical Information - NSCIA, 8/95
Although
there is more information available about people who have a spinal
cord injury than ever before, much of it is incomplete. Some of the
statistical data is summarized below per 8/95.
Number
of New Injuries Per Year
32
injuries per million population or 7800 injuries in the US each year
Most
researchers feel that these numbers represent significant under-
reporting. Injuries not recorded include cases where the patient
instantaneously or soon after the injury, cases with little or no
remaining neurological deficit, and people who have neurologic
problems secondary to trauma, but are not classified as SCI.
Researchers estimate that an additional 20 cases per million (4860
per year) die before reaching the hospital.
Total
Number of People with SCI
- 82% male, 18% female
- Highest per capita rate of injury occurs between ages 16-30
- Average age at injury - 33.4
- Median age at injury - 26
- Mode (most frequent) age at injury 19
- Motor vehicle accidents are the leading cause of SCI (44%), followed by acts of violence (24%),falls (22%) and sports (8%), other (2%)
- 2/3 of sports injuries are from diving
- Falls overtake motor vehicles as leading cause after age 45
- Acts of violence and sports cause less injuries as age increases
- Acts of violence have overtaken falls as the second most common source of spinal cord injury
- Marital status at injury:
- Single 53%
- Married 31%
- Divorced 9%
- Other 7%
- 5 years post-injury:
- 88% of single people with SCI were still single vs. 65% of the non-SCI population
- 81% of married people with SCI were still married vs. 89% of the non-SCI population
- Employment status among persons between 16 and 59 years of age at injury:
- Employed 58.8%
- Unemployed 41.2%
(includes: students, retired, and homemakers)
- Employed 8 years post-injury:
- Paraplegic 34.4%
- Quadriplegic 24.3%
People
who return to work in the first year post-injury usually return to
the same job for the same employer. People who return to work after
the first year post-injury either worked for different employers or
were students who found work.
How
are spinal injuries caused?
Until
the most recent figures were released by NSCIA in August, 1995,
these were considered as the major causes of spinal cord injuries.
See Answer to # 4 and Dr. Wise YoungÃs statistics in Section 2 for
all the most recent demographics. One of the most surprising
findings is that acts of violence have now overtaken falls as
the second most common source of spinal cord injury, as of
the 1995 findings.
Previous
To 1995:
- Motor vehicles 48%
- Falls 21%
- Sports 14% (66% of which are caused in diving accidents)
- Violence 15%
- Other 2%
The
Injury
Since
1988, 45% of all injuries have been complete, 55% incomplete.
Complete injuries result in total loss of sensation and function
below the injury level. Incomplete injuries result in partial loss.
"Complete" does not necessarily mean the cord has been
severed. Each of the above categories can occur in paraplegia and
quadriplegia.
Except
for the incomplete-Preserved motor (functional), no more than 0.9%
fully recover, although all can improve from the initial diagnosis.
Overall,
slightly more than 1/2 of all injuries result in quadriplegia.
However, the proportion of quadriplegics increase markedly after age
45, comprising 2/3 of all injuries after age 60 and 87% of all
injuries after age 75.
92% of all sports injuries result in quadriplegia.
92% of all sports injuries result in quadriplegia.
Most
people with neurologically complete lesions above C-3 die before
receiving medical treatment. Those who survive are usually dependent
on mechanical respirators to breathe.
50%
of all cases have other injuries associated with the spinal cord
injury.
Most
Frequent Neurological Category
Quadriplegia,
incomplete 31.2%
Paraplegia, complete 28.2%
Paraplegia, incomplete 23.1%
Quadriplegia, complete 17.5%
Paraplegia, complete 28.2%
Paraplegia, incomplete 23.1%
Quadriplegia, complete 17.5%
Hospitalization
(Important:
This section applies only to individuals who were admitted to one of
the hospitals designated as "Model" SCI centers by the
National Institute of Disability and Rehabilitation Research.)
Over
37% of all cases admitted to the Spinal Cord Injury System sponsored
by the NIDRR arrive within 24 hours of injury. The mean time between
injury and admission is 6 days.
Only
10-15% of all people with injuries are admitted to the NIDRR SCI
system. The remainder go to CARF facilities or to general hospitals
in their local community.
It is
now known that the length of stay and hospital charges for acute care
and initial rehabilitation are higher for cases where admission to
the SCI system is delayed beyond 24 hours. Average length of stay
(1992):
Quadriplegics
95 days
Paraplegics 67 days
All 79 days
Paraplegics 67 days
All 79 days
Average
charges (1990 dollars) Note: Specific cases are considerably higher.
Quadriplegics
$118,900
Paraplegics $ 85,100
All $ 99,553
Paraplegics $ 85,100
All $ 99,553
Source
of payment acute care:
Private
Insurance 53%
Medicaid 25%
Self-pay 1%
Vocational Rehab 14%
Worker's Comp 12%
Medicare 5%
Other 2%
Medicaid 25%
Self-pay 1%
Vocational Rehab 14%
Worker's Comp 12%
Medicare 5%
Other 2%
Ongoing
medical care: (Many people have more than one source of payment.)
Private
Insurance 43%
Medicare 25%
Self-pay 2%
Medicaid 31%
Worker's Compensation 11%
Vocational Rehab 16%
Medicare 25%
Self-pay 2%
Medicaid 31%
Worker's Compensation 11%
Vocational Rehab 16%
After
the Hospital
Residence
at discharge
Private
Residence 92%
Nursing Home 4%
Other Hospital 2%
Group Home 2%
Nursing Home 4%
Other Hospital 2%
Group Home 2%
There
is no apparent relationship between severity of injury and nursing
home admission, indicating that admission is caused by other factors
(i.e. family can't take care of person, medical complications, etc.)
Nursing home admission is more common among elderly persons.
Each
year 1/3 to 1/2 of all people with SCI are re-admitted to the
hospital. There is no difference in the rate of re-admissions between
persons with paraplegia and quadriplegia, but there is a difference
between the rate for those with complete and incomplete injuries.
Survival
Overall,
85% of SCI patients who survive the first 24 hours are still alive 10
years later, compared with 98% of the non-SCI population given
similar age and sex.
Causes
of Death
The
most common cause of death is respiratory ailment, whereas, in the
past it was renal failure. An increasing number of people with SCI
are dying of unrelated causes such as cancer or cardiovascular
disease, similar to that of the general population. Mortality rates
are significantly higher during the first year after injury than
during subsequent years.
http://www.sci-info-pages.com/facts.html
http://www.sci-info-pages.com/facts.html
Spinal Cord Injury Levels & Classification
Wise
Young, Ph.D., M.D.W.
M. Keck Center for Collaborative Neuroscience
Rutgers University, Piscataway, NJ
Rutgers University, Piscataway, NJ
When
people are injured, they are often told that they have an injury at a
given spinal cord level and are given a qualifier indicating the
severity of injury, i.e. "complete" or "incomplete".
They may also be told that they are classified according to the
American Spinal Injury Association (ASIA) Classification, as a ASIA
A, B, C, or D. They may also be told that they have a bony fracture
or involvement of one or more spinal segments or vertebral levels.
What most people do not know is doctors are frequently confused about
the definition of spinal cord injury levels, the definition of
complete and incomplete injury, and the classification of spinal cord
injury. In the early 1990's, when I co-chaired the committee that
helped define the currently accepted ASIA Classification, there was
no single definition of level, completeness of injury, or
classification. In this article, I will briefly address the issue of
spinal cord injury levels, the definition of "complete"
spinal cord injury, and the ASIA Classification approach towards
spinal cord injury.
Vertebral vs. Cord Segmental Levels
The
spinal cord is situated within the spine. The spine consists of a
series of vertebral segments. The spinal cord itself has
"neurological" segmental levels which are defined by the
spinal roots that enter and exist the spinal column between each of
the vertebral segments. As shown in the figure the spinal cord
segmental levels do not necessarily correspond to the bony segments.
The vertebral levels are indicated on the left side while the cord
segmental levels are listed for the cervical (red), thoracic (green),
lumbar (blue), and sacral (yellow) cord.
Vertebral
segments. There
are 7 cervical (neck), 12 thoracic (chest), 5 lumbar (back), and 5
sacral (tail) vertebrae. The thoracic vertebrae are defined by The
spinal cord segments are not necessarily situated at the same
vertebral levels. For example, while the C1 cord is located at the C1
vertebra, the C8 cord is situated at the C7 vertebra. While the T1
cord is situated at the T1 vertebra, the T12 cord is situated at the
T8 vertebra. The lumbar cord is situated between T9 and T11
vertebrae. The sacral cord is situated between the T12 to L2
vertebrae.
Spinal
Roots. The
spinal roots for C1 exit the spinal column at the atlanto-occiput
junction. The spinal roots for C2 exit the spinal column at the
atlanto-axis. The C3 roots exit between C2 and C3. The C8 root exits
between C7 and C8. The first thoracic root or T1 exits the spinal
cord between T1 and T2 vertebral bodies. The T12 root exits the
spinal cord between T1 and L1. The L1 root exits the spinal cord
between L1 and L2 bodies. The L5 root exits the cord between L1 and
S1 bodies.
The
Cervical Cord. The
first and second cervical segments are special because this is what
holds the head. The lower back of the head is called the Occiput. The
first cervical vertebra, upon which the head is perched is sometimes
called Atlas, after the Greek mythological figure who held up earth.
The second cervical vertebra is sometimes called the Axis, upon which
Atlas pivots. The interface between the occiput and the atlas is
therefore called the atlanto-occiput junction. The interface between
the first and second vertebra is called the atlanto-axis junction.
The C3 cord contains the phrenic nucleus. The cervical cord
innervates the deltoids (C4), biceps (C4-5), wrist extensors (C6),
triceps (C7), wrist extensors (C8), and hand muscles (C8-T1).
The
Thoracic Cord. The
thoracic vertebral segments are defined by those that have a rib.
These vertebral segments are also very special because they form the
back wall of the pulmonary cavity and the ribs. The spinal roots form
the intercostal (between the ribs) nerves that run on the bottom side
of the ribs and these nerves control the intercostal muscles and
associated dermatomes.
The
Lumbosacral Cord. The
lumbosacral vertebra form the remainder of the segments below the
vertebrae of the thorax. The lumbosacral spinal cord, however, starts
at about T9 and continues only to L2. It contains most of the
segments that innervate the hip and legs, as well as the buttocks and
anal regions.
The
Cauda Equina. In
human, the spinal cord ends at L2 vertebral level. The tip of the
spinal cord is called the conus. Below the conus, there is a spray of
spinal roots that is frequently called the cauda equina or horse's
tail. Injuries to T12 and L1 vertebra damage the lumbar cord.
Injuries to L2 frequently damage the conus. Injuries below L2 usually
involve the cauda equina and represent injuries to spinal roots
rather than the spinal cord proper.
In
summary, spinal vertebral and spinal cord segmental levels are not
necessarily the same. In the upper spinal cord, the first two
cervical cord segments roughly match the first two cervical vertebral
levels. However, the C3 through C8 segments of the spinal cords are
situated between C3 through C7 bony vertebral levels. Likewise, in
the thoracic spinal cord, the first two thoracic cord segments
roughly match first two thoracic vertebral levels. However, T3
through T12 cord segments are situated between T3 to T8. The lumbar
cord segments are situated at the T9 through T11 levels while the
sacral segments are situated from T12 to L1. The tip of the spinal
cord or conus is situated at L2 vertebral level. Below L2, there is
only spinal roots, called the cauda equina.
Sensory versus Motor Levels
A
dermatome is a patch of skin that is innervated by a given spinal
cord level. Figure 2 is taken from the ASIA classification manual,
obtainable from the ASIA web site. Each dermatome has a specific
point recommended for testing and shown in the figure. After injury,
the dermatomes can expand or contract, depending on plasticity of the
spinal cord.
C2
to C4. The
C2 dermatome covers the occiput and the top part of the neck. C3
covers the lower part of the neck to the clavicle (the horizontal
bone that goes to the shoulder. C4 covers the area just below the
clavicle.
C5
to T1. These
dermatomes are all situated in the arms. C5 covers the lateral arm at
and above the elbow. C6 covers the forearm and the radial (thumb)
side of the hand. C7 is the middle finger, C8 is the lateral aspects
of the hand, and T1 covers the medial side of the forearm.
T2
to T12. The
thoracic covers the axillary and chest region. T3 to T12 covers the
chest and back to the hip girdle. The nipples are situated in the
middle of T4. T10 is situated at the umbilicus. T12 ends just above
the hip girdle.
L1
to L5. The
cutaneous dermatome representating the hip girdle and groin area is
innervated by L1 spinal cord. L2 and 3 cover the front part of the
thighs. L4 and L5 cover medial and lateral aspects of the lower leg.
S1
to S5. S1
covers the heel and the middle back of the leg. S2 covers the back of
the thighs. S3 cover the medial side of the buttocks and S4-5 covers
the perineal region. S5 is of course the lowest dermatome and
represents
the skin immediately at and adjacent to the anus.
Ten
muscle groups represent
the motor innervation by the cervical and lumbosacral spinal cord.
The ASIA system does not include the abdominal muscles (i.e. T10-11)
because the thoracic levels are much easier to determine from sensory
levels. It also excludes certain muscles (e.g. hamstrings) because
the segmental levels that innervate them are already represented by
other muscles.
Arm
and hand muscles. C5
represents the elbow flexors (biceps), C6 the wrist extensors, C7 the
elbow extensors (triceps), C8 the finger flexors, and T1 the little
finger abductor (outward movement of the pinky finger).
Leg
and foot muscles. The
leg muscles represent the lumbar segments, i.e. L2 are the hip
flexors (psoas), L3 the knee extensors (quadriceps), L4 the ankle
dorsiflexors (anterior tibialis), L5 the long toe extensors (hallucis
longus), S1 the ankle plantar flexors (gastrocnemius).
The
anal sphincter is
innervated by the S4-5 cord and represents the end of the spinal
cord. The anal sphincter is a critical part of the spinal cord injury
examination. If the person has any voluntary anal contraction,
regardless of any other finding, that person is by definition a motor
incomplete injury.
It is
important to note that the muscle groups specified in the ASIA
classifications represent a gross over simplication of the situation.
Almost every muscle received innervation from two or more segments.
In
summary,
the spinal cord segment serve specific motor and sensory regions of
the body. The sensory regions are called dermatomes with each segment
of the spinal cord innervating a particularly area of skin. The
distribution of these dermatomes are relatively straightforward
except on the limbs. In the arms, the cervical dermatomes C5 to T1
are arrayed from proximal radial (C5) to distal (C6-8) and proximal
medial (T1). In the legs, the L1 to L5 dermatomes cover the front of
the leg from proximal to distal while the sacral dermatomes cover the
back of the leg.
Spinal Cord Injury Levels
Differences
between neurological and rehabilitation definitions of spinal cord
injury levels.
Doctors
use two different definitions for spinal cord injury levels. Given
the same neurological examination and findings, neurologists and
physiatrists may not assign the same spinal cord injury level. In
general, neurologists define the level of injury as the first spinal
segmental level that shows abnormal neurological loss. Thus, for
example, if a person has loss of biceps, the motor level of the
injury is often said to be C4. In contrast, physiatrists or
rehabilitation doctors tend to define level of injury as the lowest
spinal segmental level that is normal. Thus, if a patient has normal
C3 sensations and absent C4 sensation, a physiatrist would say the
sensory level is C3 whereas a neurologist or neurosurgeon would call
it a C4 injury level. Most orthopedic surgeons tend to refer to the
bony level of injury as the level of injury.
EXAMPLE. The
most common cervical spinal injuries involve C4 or C5. Take, for
example, a person who has had a burst fracture of the C5 vertebral
body. A burst fracture usually indicates severe trauma to vertebral
body that typically injures the C6 spinal cord situated at the C5
vertebrae and also the C4 spinal roots that exits the spinal column
between the C4 and C5 vertebra. Such an injury should cause a loss of
sensations in C4 dermatome and weak deltoids (C4) due to injury to
the C4 roots. Due to edema (swelling of the spinal cord), the biceps
(C5) may be initially weak but should recover. The wrist extensors
(C6), however, should remain weak and sensation at and below C6
should be severely compromised. A neurosurgeon or neurologist
examining the above patient usually would conclude that there is a
burst fracture at C5 from the x-rays, an initial sensory level at C4
(the first abnormal sensory dermatome) and the partial loss of
deltoids and biceps would imply a motor level at C4 (the highest
abnormal muscle level). Over time, as the patient recovers the C4
roots and the C5 spinal cord, both the sensory level and motor level
should end up at C6. Such recovery is often attributed to "root"
recovery. On the other hand, a physiatrist would conclude that the
patient initially has a C3 sensory level, a C4 motor level, and a C5
vertebral injury level. If the patient recovers the C4 root and the
C5 cord, the physiatrist would conclude that both the sensory and
motor levels are C5.
Discrepant
lower thoracic vertebral and cord levels. The
spinal vertebral and cord segmental levels become increasingly
discrepant further down the spinal column. For example, a T8
vertebral injury will result in a T12 spinal cord or neurological
level. A T11 vertebral injury, in fact, will result in a L5 lumbar
spinal cord level. Most patients and even many doctors do not
understand how discrepant the vertebral and spinal cord levels can
get in the lower spinal cord.
EXAMPLE. The
most common thoracic spinal cord injury involves T11 and T12. A
patient with a T11 vertebral injury may have or recover sensations in
the L1 through L4 dermatomes which include the front of the leg down
to the mid-shin level. In addition, such a patient should recover hip
extensors, knee extensors, and even ankle dorsiflexion. However, the
sacral functions, including bowel and bladder and many of the flexor
functions of the leg may be absent or weak. As in the case of
cervical and thoracic spinal cord injury, it is important to assess
both sensory and motor function.
Conus
and Cauda Equina Injuries. Injuries
to the spinal column at L2 or lower will damage the tip of the spinal
cord, called the conus, or the spray of spinal roots that are
descending to the appropriate spinal vertebral levels to exit the
spinal canal or the caudal equina. Please note that the spinal roots
for L2 through S5 all descend in the cauda equina and injury to these
roots would disrupt sensory and motor fibers from these segments.
Strictly speaking, the spinal roots are part of the peripheral
nervous system as opposed to the spinal cord. Peripheral nerves are
supposed to be able to regenerate to some extent. However, the spinal
roots are different from peripheral nerves in two respects. First,
the neurons from which sensory axons emanate are situated in the
dorsal root ganglia (DRG) which are located just outside the spinal
column. One branch of the DRG goes into the spinal cord (called the
central branch) and the other is the peripheral branch.
Thus,
a spinal root injury is damaging the central branch of the sensory
nerve whereas peripheral nerve injury usually damages the peripheral
branch. The sensory axon must grow back into the spinal cord in order
to restore function and they generally will not do so because of
axonal growth inhibitors in the spinal cord and particular at the
so-called PNS-CNS junction at the dorsal root entry zone. Second, the
cauda equina contains the ventral roots of the spinal cord, through
which the motor axons of the spinal cord pass to innervate muscles.
If the injury to the ventral root is close to the motoneurons that
sent the axons, the injury may damage the motoneuron itself. Both of
these factors significantly reduce the likelihood of neurological
recovery in a cauda equina injury compared to a peripheral nerve
injury.
Complete versus Incomplete Injury
Most
clinicians commonly describe injuries as "complete" or
"incomplete".
Traditionally,
"complete" spinal cord injury means having no voluntary
motor or conscious sensory function below the injury site. However,
this definition is often difficult to apply. The following three
example illustrate the weaknesses and ambiguity of the traditional
definition. The ASIA committee considered these questions when it
formulated the classification system for spinal cord injury in 1992.
- Zone of partial preservation. Some people have some function for several segments below the injury site but below which no motor and sensory function was present. This is in fact rather common. Many people have zones of partial preservation. Is such a person "complete" or "incomplete", and at what level?
- Lateral preservation. A person may have partial preservation of function on one side but not the other or at a different level. For example, if a person has a C4 level on one side and a T1 level on the other side, is the person complete and at what level?
- Recovery of function. A person may initially have no function below the injury level but recovers substantial motor or sensory function below the injury site. Was that person a "complete" spinal cord injury and became "complete"? This is not a trivial question because if one has a clinical trial that stipulates "complete" spinal cord injuries, a time must be stipulated for when the status was determined.
Most
clinicians would regard a person as complete if the person has any
level below which no function is present. The ASIA Committee decided
to take this criterion to its logical limit, i.e. if the person has
any spinal level below which there is no neurological function, that
person would be classified as a "complete" injury. This
translates into a simple definition of "complete" spinal
cord injury: a person is a "complete" if they do not have
motor and sensory function in the anal and perineal region
representing the lowest sacral
cord
(S4-S5).
The
decision to make the absence and presence of function at S4-5 the
definition for "complete" injury not only resolved the
problem of the zone of partial preservation but lateral preservation
of function but it also resolved the issue of recovery of function.
As it turns out, very few patients who have loss of S4/5 function
recovered such function spontaneously. As shown in figure 3 below,
while this simplifies the criterion for assessing whether an injury
is "complete", the ASIA classification committee decided
that both motor and sensory levels should be expressed on each side
separately, as well as the zone of partial preservation.
In
the end, the whole issue of "complete" versus "incomplete"
injury may be a moot issue. The absence of motor and sensory function
below the injury site does not necessarily mean that there are no
axons that cross the injury site. Many clinicians equate a "complete"
spinal cord injury with the lack of axons crossing the injury site.
However, much animal and clinical data suggest that an animal or
person with no function below the injury site can recover some
function when the spinal cord is reperfused (in the case of an
arteriovenous malformation causing ischemia to the cord),
decompressed (in the case of a spinal cord that is chronically
compressed), or treated with a drug such as 4-aminopyridine. The
labeling of a person as being "complete" or "incomplete",
in my opinion, should not be used to deny a person hope or therapy.
Classification of Spinal Cord Injury Severity
Clinicians
have long used a clinical scale to grade severity of neurological
loss. First devised at Stokes Manville before World War II and
popularized by Frankel in the 1970's, the original scoring approach
segregated patients into five categories, i.e. no function (A),
sensory only (B), some sensory and motor preservation (C), useful
motor function (D), and normal (E).
The
ASIA Impairment Scale is follows the Frankel scale but differs from
the older scale in several important respects. First, instead of no
function below the injury level, ASIA A is defined as a person with
no motor or sensory function preserved in the sacral segments S4-S5.
This definition is clear and unambiguous. ASIA B is essentially
identical to Frankel B but adds the requirement of preserved sacral
S4-S5 function. It should be noted that ASIA A and B classification
depend entirely on a single observation, i.e. the preservation of
motor and sensory function of S4-5.
The
ASIA scale also added quantitive criteria for C and D. The original
Frankel scale asked clinicians to evaluate the usefulness of lower
limb function. This not only introduced a subjective element to the
scale but ignored arm and hand function in patients with cervical
spinal cord injury. To get around this problem, ASIA stipulated that
a patient would be an ASIA C if more than half of the muscles
evaluated had a grade of less than 3/5. If not, the person was
assigned to ASIA D.
ASIA
E is of interest because it implies that somebody can have spinal
cord injury without having any neurological deficits at least
detectable on a neurological examination of this type. Also, the ASIA
motor and sensory scoring may not be sensitive to subtle weakness,
presence of spasticity, pain, and certain forms of dyesthesia that
could be a result of spinal cord injury. Note that such a person
would be categorized as an ASIA E.
These
changes in the ASIA scale significantly improved the reliability and
consistency of the classification. Although it was more logical, the
new definition of "complete" injury does not necessarily
mean that it better reflects injury severity. For example, is there
any situation where a person could be an ASIA B and better off the
ASIA C or even ASIA D?
The
new ASIA A categorization turns out to be more predictive of
prognosis than the previous definition where the presence of function
several segments below the injury site but the absence of function
below a given level could be interpreted as an "incomplete"
spinal cord injury.
The
ASIA committee also classified incomplete spinal cord injuries into
five types. A central cord syndrome is associated with greater loss
of upper limb function compared to the lower limbs. The Brown-Sequard
syndrome results from a hemisection lesion of the spinal cord.
Anterior cord syndrome occurs when the injury affects the anterior
spinal tracts, including the vestibulospnal tract. Conus medullaris
and cauda equina syndromes occur with damage to the conus or spinal
roots of the cord.
Conclusion
Much
confusion surrounds the terminology associated with spinal cord
injury levels, severity, and classification. The American Spinal
Injury Association tried to sort some of these issues and standardize
the language that is used to describe spinal cord injury. The ASIA
Spinal Cord Injury Classification approach has now been adopted by
almost every major organization associated with spinal cord injury.
This has resulted in more consistent terminology being used to
/describe the findings in spinal cord injury around the world.
Sci-info-pages.com/levels.html
Functional Goals
Level |
Abilities |
Functional Goals |
|
C1-C3 |
Limited
movement of head and neck |
Breathing: Depends
on a ventilator for breathing. |
|
Communication: Talking
is sometimes difficult, very limited or impossible. If ability to
talk is limited, communication can be accomplished independently
with a mouth stick and assistive technologies like a computer for
speech or typing. Effective verbal communication allows the
individual with SCI to direct caregivers in the person's daily
activities, like bathing, dressing, personal hygiene, transferring
as well as bladder and bowel management. |
||
|
Daily
tasks: Assistive
technology allows for independence in tasks such as turning pages,
using a telephone and operating lights and appliances. |
||
|
Mobility: Can
operate an electric wheelchair by using a head control, mouth
stick, or chin control. A power tilt wheelchair also for
independent pressure relief. |
||
|
|
||
|
C3-C4 |
Usually
has head and neck control. Individuals at C4 level may shrug their
shoulders. |
Breathing: May
initially require a ventilator for breathing, usually adjust to
breathing full-time without ventilator assistance. |
|
Communication: Normal. |
||
|
Daily
tasks: With
specialized equipment, some may have limited independence in
feeding and independently operate an adjustable bed with an
adapted controller. |
||
|
|
||
|
C5 |
Typically
has head and neck control, can shrug shoulder and has shoulder
control. Can bend his/her elbows and turn palms face up. |
Daily
tasks: Independence
with eating, drinking, face washing, brushing of teeth, face
shaving and hair care after assistance in setting up specialized
equipment. |
|
Health
care: Can
manage their own health care by doing self-assist coughs and
pressure reliefs by leaning forward or side -to-side. |
||
|
Mobility: May
have strength to push a manual wheelchair for short distances over
smooth surfaces. A power wheelchair with hand controls is
typically used for daily activities. Driving may be possible after
being evaluated by a qualified professional to determine special
equipment needs. |
||
|
|
||
|
C6 |
Has
movement in head, neck, shoulders, arms and wrists. Can shrug
shoulders, bend elbows, turn palms up and down and extend
wrists. |
Daily
tasks: With
help of some specialized equipment, can perform with greater ease
and independence, daily tasks of feeding, bathing, grooming,
personal hygiene and dressing. May independently perform light
housekeeping duties. |
|
Health
care: Can
independently do pressure reliefs, skin checks and turn in bed. |
||
|
Mobility: Some
individuals can independently do transfers but often require a
sliding board. Can use a manual wheelchair for daily activities
but may use power wheelchair for greater ease of independence. |
||
|
|
||
|
C7 |
Has
similar movement as an individual with C6, with added ability to
straighten his/her elbows. |
Daily
tasks: Able
to perform household duties. Need fewer adaptive aids in
independent living. |
|
Health
care: Able
to do wheelchair pushups for pressure reliefs. |
||
|
Mobility: Daily
use of manual wheelchair. Can transfer with greater ease. |
||
|
|
||
|
C8-T1 |
Has
added strength and precision of fingers that result in limited or
natural hand function. |
Daily
tasks: Can
live independently without assistive devices in feeding, bathing,
grooming, oral and facial hygiene, dressing, bladder management
and bowel management. |
|
Mobility: Uses
manual wheelchair. Can transfer independently. |
||
|
|
||
|
T2-T6 |
Has
normal motor function in head, neck, shoulders, arms, hands and
fingers. Has increased use of rib and chest muscles, or trunk
control. |
Daily
tasks: Should
be totally independent with all activities. |
|
Mobility: A
few individuals are capable of limited walking with extensive
bracing. This requires extremely high energy and puts stress on
the upper body, offering no functional advantage. Can lead to
damage of upper joints. |
||
|
|
||
|
T7-T12 |
Has
added motor function from increased abdominal control. |
Daily
tasks: Able
to perform unsupported seated activities. |
|
Mobility: Same
as above. |
||
|
Health
care: Has
improved cough effectiveness. |
||
|
|
||
|
L1-L5 |
Has
additional return of motor movement in the hips and knees. |
Mobility: Walking
can be a viable function, with the help of specialized leg and
ankle braces. Lower levels walk with greater ease with the help of
assistive devices. |
|
|
||
|
S1-S5 |
Depending
on level of injury, there are various degrees of return of
voluntary bladder, bowel and sexual functions. |
Mobility: Increased
ability to walk with fewer or no supportive devices. |
TR
Implications
Stress reduction
- Reducing stress can improve physical and mental well-being.
Overall well-being
-
People with spinal cord injuries who participate in active recreational activities
have fewer SCI-relatedhealth problems, such as skin breakdown.
Social contacts
-Participation in community based
and group activities can help a person with a
spinal cord injuryovercome feelings of social isolation and self-consciousness.
Increased endurance
-Participation in active recreational activities increase your cardiovascular
endurance, which cangive you more energy for
returning to work or school.
Skill development
-Participation in recreational activities can enhance skills, such as fine motor use
and sitting balance,
which are used in other areas of life, such as dressing.
Increase confidence and self-esteem
Independence in recreational activities can increase
independence in other activities.
interpersonal skills Communication skills, such as assertiveness,
can be practiced in the
non-threatening environment ofrecreational activities.
Community reintegration Independence in mobility and social interaction, which can be
achieved
through recreationparticipation, leads to increased self confidence and self reliance
Adaptive
Technologies
Assistive Technology
Resources for SCI
Hospitals and Rehabilitation Centers
- http://www.sci-info-pages.com/rehabs.html - This website provides a listing for spinal cord injury hospitals and rehabilitation centers for many of the United States.
Support and Financial Assistance
- http://www.sci-info-pages.com/spinal-cord-injury-help.php - Many organizations exist to provide individuals living with spinal cord injuries and family members of those individuals with grants, equipment donations and other supports.
State Resources
Medical, Rehabilitation and Nurses Aids
- Aging With Spinal Cord Injury
Craig Hospital focuses on different body systems, how a person with SCI, and how SCI may modify the aging process. - Back and Neck Disorders Sourcebook
Basic information about disorders and injuries of the spinal cord and vertebrae, including facts on chiropractic. - Basic and Clinical Anatomy of the Spine, Spinal Cord, and ANS
Textbook on the anatomy of the spine, spinal cord, and autonomic nervous system, for students in chiropractic, osteopathy, or physical therapy. - Catastrophic Injuries in High School and College Sports (Hk Sport Science Monograph Series, V. 8)
Discusses the results of a 10-year study of serious injury among young athletes, providing recommendations for reducing catastrophic injuries, preventing deaths, and making sports programs safer. - Diagnosis and Management of Disorders of the Spinal Cord
Review of current clinical literature for neurologists of spinal cord disorders. - Functional Electrical Rehabilitation: Technological Restoration After Spinal Cord Injury
Development over the past decade of functional electrical rehabilitation. It shows how paralyzed muscle can be stimulated to perform in the physical reconditioning of an afflicted person. - Functional Electrical Stimulation: Standing and Walking After SCI
Covers the fundamental knowledge and principles of functional electrical stimulation as applied to the spinal cord injured patient. - In Search of the Lost Cord: Solving the Mystery of Spinal Cord Regeneration
Presents a history of research and provides insight into current developments that may offer the paralyzed hope for the future. - Management of Spinal Cord Injuries: A Guide for Physiotherapists
For students and junior physiotherapists with little experience in the area of spinal cord injury and a general understanding of the principles of physiotherapy. Also a useful tool for experienced clinicians. - Management of Spinal Cord Injury
Textbook for rehabilitation nurses and other rehabilitation specialists. A "Must read" for nurses working in Spinal Cord Injury areas - acute or rehab. - Neurobiology of Spinal Cord Injury (Contemporary Neuroscience)
Covers the major areas of basic science research in which progress is currently being made in the battle against the problem of spinal cord injury. - Nursing Practice Related to Spinal Cord Injury and Disorders: A Core Curriculum
A comprehensive tool for educating a broad audience of nurses in areas ranging from emergency nursing to rehabilitation. - Nursing Spinal Cord Injuries
Composed of articles written by trained spinal cord injury nurse practitioners, offers valuable insights and practical information on the rehabilitation period and its critical aspects. A reference and teaching tool for victims and their families as well as to medical professionals. - Outcome After Head, Neck and Spinal Trauma: A Medicolegal Guide
Text on the principles and clinical assessment of cranio-spinal trauma. For physicians who must provide medical reports or act as expert witnesses for possible outcomes/prognoses of injury. - Spinal Cord Injury: A Guide to Functional Outcomes in Occupational Therapy The Rehabilitation Institute of Chicago Publication Series explains spinal cord injuries in great detail.
- Spinal Cord Injury: Clinical Outcomes from the Model Systems
University of Alabama, Birmingham. Clinical research on the rehabilitation of spinal cord injury drawn from the Model Systems Uniform Database. - Spinal Cord Injury: Functional Rehabilitation (2nd Edition)
Clinical and basic research developments and includes strategies for delivering quality rehabilitative services. - Spinal Cord Injury: Medical Management and Rehabilitation
Rehabilitation Institute of Chicago, Illinois. Manual for the physicians, nurses, and physical or occupational therapists on the spinal cord injury team on maximizing the outcome potential of the spinal cord injury patient. - The Child With a Spinal Cord Injury
Provides 68 sections on etiology and prevention, management, medical issues, orthopedic problems, upper extremity management, rehabilitation, discharge and transition, habilitation, research and technological applications, and special considerations. - The Quest for Cure: Restoring Function After Spinal Cord Injury
Published by Paralyzed Veterans of America, Research & Education Department.
Spinal Cord Injury Associations & Organizations (USA)
American
Spinal Injury Association (ASIA)
Group of medical and other professionals engaged in treatment of spinal cord injury: to promote and establish standards for health care, education, to foster research and to facilitate communication between members.
Group of medical and other professionals engaged in treatment of spinal cord injury: to promote and establish standards for health care, education, to foster research and to facilitate communication between members.
Canadian
& American Spinal Research Organization
An alliance of the CSRO and ASRO to help us maximize research and the fund raising efforts. Dedicated to the improvement of the physical quality of life for persons with a spinal cord injury through targeted medical and scientific research.
An alliance of the CSRO and ASRO to help us maximize research and the fund raising efforts. Dedicated to the improvement of the physical quality of life for persons with a spinal cord injury through targeted medical and scientific research.
Center
for Paralysis Research
The Center for Paralysis Research at Purdue University was founded to both develop and test promising methods of treatment for spinal cord injuries.
The Center for Paralysis Research at Purdue University was founded to both develop and test promising methods of treatment for spinal cord injuries.
Christopher
& Dana Reeve Foundation
A merger of the American Paralysis Association and the Christopher Reeve Foundation. Supports research to develop effective treatments and a cure for paralysis caused by spinal cord injury. Includes the Paralysis Resouce Center which provides a comprehensive, national source of information for people living with paralysis and their caregivers to promote health, foster involvement in the community, and improve quality of life.
A merger of the American Paralysis Association and the Christopher Reeve Foundation. Supports research to develop effective treatments and a cure for paralysis caused by spinal cord injury. Includes the Paralysis Resouce Center which provides a comprehensive, national source of information for people living with paralysis and their caregivers to promote health, foster involvement in the community, and improve quality of life.
Darrell
Gwynn Foundation
Exists to prevent, provide for and ultimately cure spinal cord injuries and other debilitating illnesses. To expedite specific cures, the Foundation assists in the funding of targeted research. Also helps improve the quality of life for those already afflicted with injury or illness, by providing necessary equipment or special services.
Exists to prevent, provide for and ultimately cure spinal cord injuries and other debilitating illnesses. To expedite specific cures, the Foundation assists in the funding of targeted research. Also helps improve the quality of life for those already afflicted with injury or illness, by providing necessary equipment or special services.
Facing
Disability
A web resource with more than 1,000 videos drawn from interviews of people with spinal cord injuries, their families, caregivers and experts.
A web resource with more than 1,000 videos drawn from interviews of people with spinal cord injuries, their families, caregivers and experts.
Foundation
for Spinal Cord Injury Prevention, Care & Cure
FSCIPCC is a non-profit educational group dedicated to the prevention, care and cure of spinal cord injuries through public awareness, education and funding research.
FSCIPCC is a non-profit educational group dedicated to the prevention, care and cure of spinal cord injuries through public awareness, education and funding research.
International
Campaign for Cure of Spinal Injury
An affiliation of organizations working to fund research into cures for paralysis caused by spinal cord injury. This site has been created as an information resource for interested individuals, organizations and governments who wish to understand more about, and perhaps, contribute to spinal cord injury research.
An affiliation of organizations working to fund research into cures for paralysis caused by spinal cord injury. This site has been created as an information resource for interested individuals, organizations and governments who wish to understand more about, and perhaps, contribute to spinal cord injury research.
Life
Rolls On
A subsidiary of the Christopher & Dana Reeve Foundation, dedicated to improving the quality of life for young people affected by spinal cord injury, and utilizes action sports as a platform to inspire infinite possibilities despite paralysis.
A subsidiary of the Christopher & Dana Reeve Foundation, dedicated to improving the quality of life for young people affected by spinal cord injury, and utilizes action sports as a platform to inspire infinite possibilities despite paralysis.
Miami
Project to Cure Paralysis
University of Miami School of Medicine, is the world's largest, most comprehensive research center dedicated to finding more effective treatments and, ultimately, a cure for paralysis that results from spinal cord injury.
University of Miami School of Medicine, is the world's largest, most comprehensive research center dedicated to finding more effective treatments and, ultimately, a cure for paralysis that results from spinal cord injury.
Mike
Utley Foundation
Committed to providing financial support of selected research, rehabilitation and education programs on spinal cord injuries. The Foundation seeks financial assistance through special events, fund-raising, and corporate and individual support throughout the United States and Canada.
Committed to providing financial support of selected research, rehabilitation and education programs on spinal cord injuries. The Foundation seeks financial assistance through special events, fund-raising, and corporate and individual support throughout the United States and Canada.
Morton
Cure Paralysis Fund
Organization dedicated to finding a cure for spinal cord injuries by raising money for spinal cord injury research. In its brief history, it has raised over $1 million despite being in all-volunteer organization. Because of that efficiency, nearly 100% of every dollar donated goes directly to research. The MCPFuses a peer review process of experts to allocate its funds to the projects that offer the most potential for moving science forward.
Organization dedicated to finding a cure for spinal cord injuries by raising money for spinal cord injury research. In its brief history, it has raised over $1 million despite being in all-volunteer organization. Because of that efficiency, nearly 100% of every dollar donated goes directly to research. The MCPFuses a peer review process of experts to allocate its funds to the projects that offer the most potential for moving science forward.
National
Spinal Cord Injury Association
Mission is to enable people with SCI to make choices and take actions to achieve their highest level of independence and personal fulfillment. Includes current articles/news, injury information, chat, message boards, a quarterly publication and other areas.
Mission is to enable people with SCI to make choices and take actions to achieve their highest level of independence and personal fulfillment. Includes current articles/news, injury information, chat, message boards, a quarterly publication and other areas.
Paralyzed
Veterans of America (PVA)
This site is a resource center for veterans and for all American with a spinal cord injury or disease, as well as their families and the professional communities who serve them.
This site is a resource center for veterans and for all American with a spinal cord injury or disease, as well as their families and the professional communities who serve them.
Rehabilitation
Research Center (RRC)
Involved in research activities to enhance the lives of those affected by SCI and TBI. Part of the Santa Clara Valley Medical Center.
Involved in research activities to enhance the lives of those affected by SCI and TBI. Part of the Santa Clara Valley Medical Center.
Roman
Reed Foundation
Provides support and funding for the research in the field of spinal cord injury and regenerative medicine — being conducted by leading universities, scientists and institutions — in the quest for a cure for paralysis.
Provides support and funding for the research in the field of spinal cord injury and regenerative medicine — being conducted by leading universities, scientists and institutions — in the quest for a cure for paralysis.
Sam
Schmidt Paralysis Foundation
Helps individuals overcome spinal cord injuries and other neurological disorders by funding scientific research, medical treatment, rehabilitation and technological advances.
Helps individuals overcome spinal cord injuries and other neurological disorders by funding scientific research, medical treatment, rehabilitation and technological advances.
Spinal
Cord and Brain Injury Research Center
Located at the University of Kentucky College of Medicine,SCoBIRC was established in 1999 to promote both individual and collaborative studies on injuries to the spinal cord and brain that result in paralysis or other loss of neurologic function.
Located at the University of Kentucky College of Medicine,SCoBIRC was established in 1999 to promote both individual and collaborative studies on injuries to the spinal cord and brain that result in paralysis or other loss of neurologic function.
Spinal
Cord Injury Information Network
Provides news and events, research projects, general information and statistics.
Provides news and events, research projects, general information and statistics.
Spinal
Cord Injury Network International (SCINI)
SCINI is a non-profit organization dedicated to facilitating access to quality health care by providing information and referral services to spinal-cord-injured individuals and their families.
SCINI is a non-profit organization dedicated to facilitating access to quality health care by providing information and referral services to spinal-cord-injured individuals and their families.
Spinal
Cord Society (SCS)
An international organization for cure research and treatment of spinal cord injury paralysis and related problems. Site includes headlines from the SCS newsletter on cure research, current SCS research projects, and other information on SCS. 100% of its research funding goes for research!
An international organization for cure research and treatment of spinal cord injury paralysis and related problems. Site includes headlines from the SCS newsletter on cure research, current SCS research projects, and other information on SCS. 100% of its research funding goes for research!
United
Spinal Association
Formerly the Eastern Paralyzed Veterans Association, a nonprofit that provides information and services to individuals with spinal cord injury and disease regarding benefits, disability rights advocacy, wheelchairs and barrier-free design.
Formerly the Eastern Paralyzed Veterans Association, a nonprofit that provides information and services to individuals with spinal cord injury and disease regarding benefits, disability rights advocacy, wheelchairs and barrier-free design.
W.
M. Keck Center for Collaborative Neuroscience
The Center is situated at Rutgers, the State University of New Jersey. The SCI Project encompasses the research program devoted to care and cure of spinal cord injury. This site describes the people, the research programs, and the mission of the Center. Also provides support and information for the community, including the forum.
The Center is situated at Rutgers, the State University of New Jersey. The SCI Project encompasses the research program devoted to care and cure of spinal cord injury. This site describes the people, the research programs, and the mission of the Center. Also provides support and information for the community, including the forum.
Spinal
Cord Injury Glossary
Abdominal
Binder -
Wide elastic binder use to help prevent a drop in blood pressure or
used for cosmetic purposes to hold in abdomen. A rigid (non-elastic)
binder is used to help empty the bladder in some patients.
Aces -
Elastic bandage used to wrap extremities to help support and prevent
blood pressure from lowering.
Acute
rehabilitation program -
Primary emphasis on the early rehabilitation phase which usually
begins as soon as a person is medically stable. The program is
designed to be comprehensive and based in a medical facility with a
typical length of stay of 2-3 months. Treatment is provided by and
identifiable team in a designated unit.
Adipose
tissue -
Fatty tissue.
ADL -
Activities of daily living: eating, dressing, grooming, shaving, etc.
Nurses, occupational and physical therapists are the main coaches for
ADL, which is sometimes called DLS or daily living skills.
Afferent -
Sensory pathway proceeding toward the central nervous system from the
peripheral receptor organs.
Ambulation -
"Walking" with braces and/or crutches.
Ankylosis -
Fixation of a joint leading to immobility, due to ossification or
bony deposits of calcium at joints.
Anterior -
The front of anything. Before or toward the front.
Anterior
Cord Syndrome -An
incomplete spinal injury in which all functions are absent below the
level of injury except proprioception and sensation.
Anterior
Spinal Artery Syndrome -
(also known as Anterior Cord Syndrome) Anterior spinal artery
syndrome refers to the anterior spinal artery that originates from
the vertebral arteries and basal artery at the base of the brain and
supplies the anterior two-thirds of the spinal cord to the upper
thoracic (chest) region. The lesion produces variable loss of motor
function and of sensitivity to pinprick and temperature, while
preserving proprioception (position sense).
Anterio-lateral -
To the front and to the side.
Antero-posterior -
To the front and to the back.
Antibody -
A protein, carried in the blood, produced by the immune to system
which will attack germs, viruses, and other invading agents.
Anticholinergic -
A drug often prescribed for those with indwelling catheters to reduce
spasms of smooth muscle, including the bladder. Anticholinergics
block certain receptors (acetylcholine), resulting in inhibition of
certain nerve impulses (parasympathetic). Brand names include
Daricon, ProBanthine, Urispas, Ditropan, and Cystospaz. Side effects
may include constipation, nausea, dry mouth, and blurred vision.
Caution: combined with alcohol, anticholinergics can cause extreme
drowsiness.
Antidepressant -
A drug prescribed to treat depression; standard tricyclic
antidepressants include Tofranil, Imvate, Elavil, Norpramin, and
Adapin.
Aphasia -
The change, or loss, in language function due to an injury.
Apraxia -
The inability to produce voluntary speech due to a deficit in motor
(muscle) programming caused by brain damage.
Arachnoid
Membrane -
The middle of three membranes protecting the brain and spinal cord.
Arachnoiditis -
Inflammation and scarring of the membranes covering the spinal cord.
ASIA
Score -
A measure of function after spinal cord injury, used by physicians.
"A" means complete injury; "E" means full
recovery.
Astrocyte -
Star-shaped glial cells which provide the necessary chemical and
physical environment for nerve regeneration.
Ataxia -
Failure or irregularity of muscle coordination.
Atelectasis -
Loss of breathing function characterized by collapsed lung tissue.
Atrophy -
A wasting away or decrease in size of a cell, tissue, organ, or part
of the body due to lack of nourishment.
Augmentative
and Alternative Communication (AAC) -
Forms of communication that supplement or enhance speech or writing,
including electronic devices, picture boards, and sign language.
Autoimmune
Response -
The body produces a response against itself.
Autonomic
Dysreflexia (Hyperreflexia) -
A syndrome attributed to interruption of spinal cord sympathetic
pathways. It is a condition that can occur in anyone who has a spinal
cord injury at or above the T6 level. It is related to disconnections
between the body below the injury and the control mechanisms for
blood pressure and heart function. It causes the blood pressure to
rise to potentially dangerous levels.
Autonomic
Nervous System -
The part of the nervous system that controls involuntary activities,
including heart muscle, glands, and smooth muscle tissue. The
autonomic nervous system is subdivided into the sympathetic and
parasympathetic systems.
Axon -
The nerve fiber that carries an impulse from the nerve cell to a
target, and also carries materials from the nerve terminals back to
the nerve cell. A long, slender part of a neuron that carries the
electrochemical signal to another neuron. It's the main or core nerve
fiber which generally conducts impulses away from the cell body.
Bacterial
infection -
Infection by minute, one-celled organisms which multiply by dividing
in one or more directions.
Balkan
Frame -
A rectangular frame which may be placed over a hospital bed to
position or increase mobility. Loops or a trapeze are often hung from
the Balkan frame to assist a patient in bed activities and wheelchair
transfers to and from the bed.
Bilateral -
Refers to using both sides of the body or extremities on both sides.
Bilateral
sensory stimulation -
Stimulation of both sides of the body simultaneously, using touch,
hearing, or vision, in order to determine whether an individual
imperceives the stimulus on one side or the other.
Bilateral
transfer -
Facilitation of performance of a task by one hand as a result of
having practiced the task with the other hand.
Biofeedback -
A process that provides sight or sound information about functions of
the body, including blood pressure, muscle tension, etc. The use of
sensory feedback to help provide some self-control over autonomic
functions, such as blood pressure.
Biotechnology -
In the most general terms, biotechnology describes guiding natural
occurrences to develop useful products. More specifically, it
involves using living organism to make products and solve problems.
Bladder
Training -
Method by which the bladder is trained to empty (micturition) without
the use of an indwelling catheter. Involves drinking measured amounts
of fluid, and allowing the bladder to fill and empty at timed
intervals. See intermittent catheterization.
Body
Jacket (TLSO) -
A support made of plastic that fits over the chest, abdomen and upper
pelvis, used to support an unstable or recently fused spine.
Bowel
program -
The establishment of a "habit program" or a specific time
to empty the bowel - also known as a "dil" - so that
regularity can be achieved.
Bradycardia -
Slow pulse (< 60 beats per minute)
Brain
stem -
Composed of midbrain, pons and medulla.
Brown-Sequard
Syndrome -
An incomplete spinal cord injury where half of the cord has been
damaged. The Brown-Sequard syndrome is caused by a functional section
of half of the spinal cord. This results in motor loss on the same
side as the lesion and sensory loss on the opposite side. This
syndrome is very often associated with fairly normal bowel and
bladder function and does not prevent the person from being able to
walk, although some functional bracing or ambulatory device such as a
cane or crutch may be necessary.
Calculi -
Stones that may form in either kidney or bladder.
Carpal
Tunnel Syndrome -
A painful disorder in the hand caused by inflammation of the median
nerve in the wrist bone.
Catheter -
A flexible rubber or plastic tube for withdrawing or introducing
fluids into a cavity of the body, usually the bladder.
CT
Scan -
Computerized axial Tomography is a cross-sectional X-ray enhancement
technique that greatly benefits diagnosis with high-resolution video
images.
Cauda
Equina -
The collection of spinal roots descending from the lower part of the
spinal cord.
Cauda
Equina Syndrome -
Injury to the nerves still within the spinal cord as they form a
"horse's tail" to exit the lumbar and spinal regions. This
usually occurs with fractures below the L2 level and results in
flaccid-type paralysis. The type of bladder and bowel impairment that
results from such an injury depends on the level of the injury and
can be problematic, particularly for women, who may have difficulty
with urinary drainage and incontinence.
Central
Cord Syndrome -
A lesion, occurring almost exclusively in the cervical region, that
produces sacral sensory sparing and greater weakness in the upper
limbs than in the lower limbs. A central cord syndrome indicates
there is an injury to the central structures of the spinal cord. This
is most commonly seen in older patients with cervical arthritis and
may occur in the absence of spinal fracture.
Central
Nervous System (CNS) -
The CNS includes the brain and spinal cord.
Cerebrospinal
Fluid (CSF) -
A colorless solution similar to plasma protecting the brain and
spinal cord from shock. A lumbar puncture (spinal tap) is used to
draw CSF.
Cervical -
The upper spine (neck) area of the vertebral column. Cervical
injuries often result in quadriplegia (tetraplegia).
Collateral
sprouting -
Intact axons located near damaged areas may sprout to reestablish
connections with, and in place of damaged areas; cannot be assured
that the new connections function exactly as their damaged neighbors
did.
Complete
Lesion -
An injury with no motor or sensory function below the area of the
spinal cord that was damaged.
Contracture -
The stiffening of a body joint to the point that it can no longer be
moved through its normal range.
Condom
Catheter -
External urine collecting device used by males.
Conus
Medullaris Syndrome -
Injury of the sacral cord (conus) and lumbar nerve roots within the
neural canal, which usually results in an areflexic bladder, bowel
and lower limbs. Sacral segments may occasionally show preserved
reflexes with higher lesions.
Creatinine
Clearance -
A 24-hour urine collection test to assess how the kidneys are
functioning.
Crede -
A technique of pressing down and inward over the bladder to
facilitate voiding. Pronounced "cruh-day."
Cyst
(post traumatic cystic myelopathy) -
A collection of fluid within the spinal cord, which may increase
pressure and lead to increased neurological deterioration, loss of
sensation, pain, and dysreflexia.
Cystogram
(CG) -
X-ray taken after injecting dye into bladder.
Cystometric
Examination -
An exam measuring the pressure of forces to empty, or resisting to
empty, the bladder.
Decubitus
Ulcer -
See pressure sore.
Demyelination -
The loss of nerve fiber "insulation" due to trauma or
disease, which reduces the ability of nerves to conduct impulses (as
in multiple sclerosis and some kinds of SCI).
Denial -
Avoiding physical or emotional conflict or loss; many rehab
professionals over-ascribe denial to their patients. Hoping for
functional improvement should not be misunderstood as denying
disability.
Dendrite -
Microscopic tree-like fibers extending from a nerve cell (neuron).
They are receptors of electrochemical nervous impulse transmissions.
A fine branching process of the nerve cell which conducts a nerve
impulse from the cell body to the structure(s) supplied by the nerve,
or toward the cell body.
Depression
(dysthymia) -
An abnormal lowering of mood of psychologic or physiologic origin
which is more prolonged than mourning and is time-limited and related
to a specific loss.
Dermatome -
A map that shows typical function for various levels of spinal cord
injury. May also refer to the area of the skin innervated by the
sensory axons with each segmental nerve (root).
Derotational
Splints -
Long splints on legs and feet used to prevent foot drop and external
rotation of the hips. These splints are used when a patient is
supine.
Disability -
Any restriction or lack (resulting from an impairment) of ability to
perform an activity in a manner or within the range considered normal
for a human being.
Discharge
Planning -
Planning and preparation for life rehab. has been completed.
DLS
(Daily Living Skills) -
See 'ADL".
Dorsal
Root -
The collection of nerves entering the dorsal section (on the back) of
a spinal cord segment.
Dura
Mater -
The outermost of three membranes protecting the brain and spinal
cord, it is tough and leather-like. The fibrous outer sheath
surrounding the brain and spinal cord.
Dysphagia -
Difficulty in swallowing.
Edema -
Swelling; most commonly present in legs and feet. Edema occurs when
the body tissues contain an excessive amount of fluid (plasma),
increasing skin sensitivity and risk of pressure sores.
Egg-crate
Mattress -
Foam mattress, resembling egg cartons, that helps distribute pressure
and prevent pressure sores.
Effector
neuron -
The output nerve component of the reflex arc which transmits a
reaction to the end of the organ to which the effector neuron
connects.
Efferent -
Motor pathway proceeding from the central nervous system toward the
peripheral end organs.
Electromyogram
(EMG) -
A test that records the responses of muscles to electrical
stimulation.
Electro-ejaculation -
A means of extracting sperm from men with erectile dysfunction by
using an electrical probe in the rectum. The sperm can be used to
fertilize eggs in the uterus or in a test tube.
Environment -
The context in which development takes place, including physical
properties of stimuli.
Exacerbation -
A recurrence or worsening of symptoms.
Extension -
Movement which brings the body or limbs into straight position.
Outward movements of body parts away from the center of the body
(straightening).
External
Continence Device (ECD) –
Male external urine control device that attaches to tip of penis.
Fairley
Test -
A urine test to determine the site of infection. For instance, it can
determine whether infection exists in the bladder only or in a kidney
as well.
FES
(Functional Electric Stimulation) -
The application of low-level, computer-controlled electric current to
the neuromuscular system, including paralyzed muscle.
Flaccidity -
A form of paralysis in which muscles are soft and limp.
Flexion -
Movement which brings body or limbs into a bent position. Inward
movements of body parts toward the center of the body (bending).
Foley
Catheter -
A rubber tube placed in the urethra, extending to the bladder, in
order to empty the bladder. It is held in place with a small
fluid-filled balloon.
Functional -
The ability to carry out a purposeful activity.
Gait
Training -
Instruction in walking, with or without equipment.
Ganglioside -
Complex, carbohydrate-rich lipids found in cell membranes, most
concentrated at the surface of brain cells.
Glial
Cells -
From the Greek for "glue," glial cells are supportive cells
associated with neurons. Astrocytes and oligodendrocytes are central
nervous system glial cells. In the peripheral nervous system the main
glial cells are called Schwann cells.
Glossopharyngeal
breathing (GPB) -
A means of forcing extra air into the lungs to expand the chest and
achieve a functional cough. Also called "frog breathing."
Halo
Traction -
The process of immobilizing the upper body and cervical spine with a
traction device. The device consists of a metal ring around the head,
held in place with pins into the skull. A supporting frame is
attached to the ring and to a body jacket or vest to provide
immobilation.
Hand
Splint -
See "tenodesis".Handicap - A disadvantage that limits or
prevents fulfillment of a role that is normal (depending on age, sex,
and social and cultural factors).
Handicap
dimensions -
Physical independence, mobility, roles and activities, social
integration, and economic self-sufficiency.
Harrington
Rods -
Metal braces fixed along the spinal column for support and
stabilization.
Hemiparesis -
Partial paralysis of loss of movement on one side of the body.
Heterotopic
Ossification (HO) -
The formation of new bone deposits in the connective tissue
surrounding the major joints, primarily the hip and knee. A disorder
characterized by the deposition of large quantities of calcium at the
site of a bone injury. Often the result of prolonged immobilization.
[heterotopic bone].
Hubbard
Tank -
A large full-body tank of water used for wound care and range of
motion.
Hydronephrosis -
A kidney distended with urine to the point that its function is
impaired. Can cause uremia, the toxic retention of blood nitrogen.
Hyperreflexia -
See "autonomic dysreflexia".
Hyperesthesia -
Grossly exaggerated tactile stimuli.
Hypothermia -
An extreme lowering of the body temperature. A technique used to cool
the spinal cord after injury.
Hypoxia -
Lack of blood oxygen due to impaired lung function.
Immune
Response -
The body's defense function that produces antibodies to foreign
antigens. It is important in organ and tissue transplantation since
the body is likely to reject new tissues.
Impairment -
Any loss or abnormality of psychological, physiological, or
anatomical structure or function.
Incomplete
Injury -
Some sensation or motor control preserved below spinal cord lesion.
Incomplete
Lesion -
A spinal cord lesion in which some sensation or muscle function below
the level of injury is preserved.
Incontinence -
Lack of bowel and/or bladder control.
Indwelling
Catheter -
A flexible tube retained in the bladder, used for continuous urinary
draining to a leg bag or other device.
Informed
Consent -
A patient's right to know the risks and benefits of a medical
procedure.
Intermittent
Catheterization (ICP) -
Using a catheter for emptying the bladder on a regular schedule. See
self-catheterization.
Intrathecal
Baclofen -
Administration of the anti-spasm drug Baclofen directly to the spinal
cord by way of a surgically implanted pump.
Intravenous
Pyelogram (IVP) -
An X-ray of the kidney to determine function.
Ischemia -
A reduction of blood flow that is thought to be a major cause of
secondary injury to the brain or spinal cord after trauma.
KUB -
An X-ray of the abdomen, showing the kidneys, ureters, and bladder.
Laminectomy -
An operation used to relieve pressure on the spinal cord, or used to
examine the extent of damage to the cord.
Late
Anterior Decompression -
Surgical procedure to reduce pressure on the spinal cord by removing
bone fragments.
Lateral -
Side.
Leg
Bag -
External bag which is strapped to the leg for collection of urine.
Lesion -
An injury or wound, any pathologic or traumatic injury to the spinal
cord.
Lipid
Peroxidation -
Lipids are the backbone of nerve cell membranes.
Lithotripsy -
A non-invasive treatment for kidney stones. Shock waves, generated
under water by a spark plug, crumble stones into pieces that will
pass with urine.
Log
Roll -
Method of turning a patient without twisting the spine, used when a
person's spine is unstable.
Lower
Motor Neurons -
These nerve fibers originate in the spinal cord and travel out of the
central nervous system to muscles in the body. An injury to these
nerve cells can destroy reflexes and may also affect bowel, bladder
and sexual function.
Lower
Motor Neuron Lesion -
Any damage to the lower motor neuron or its axon (peripheral nerve)
that separates the lower motor neuron from control of its muscle
fibers. This type of lesion leads to flaccidity and muscle atrophy.
Lumbar -
Pertaining to that area immediately below the thoracic spine; the
strongest part of the spine, the lower back.
Malingering -
Faking or conscious deception; voluntary production of symptoms for a
rationally considered goal, such as financial recompense, avoidance
of responsibility, etc.
Medicaid -
A state-funded insurance program that varies by state, and may vary
within a state if a managed care product is present. Individuals are
eligible and can receive the insurance for free if they meet maximal
income limits, are pregnant, are <21 years of age, or have
sufficient enough medical bills. Pays for all rehabilitation care,
equipment, custodial and skilled nursing home care, home personal
care services, and medications (a co-pay is usually needed for
medications). All Medicaid in Virginia is managed care (as of 4/99).
Medicare -
A Federally-funded insurance program that offers standard services
nationwide, that may vary if a managed care product is present.
Individuals are eligible and can receive for free Part A (pays for
inpatient care, all rehabilitation care, equipment) if they have been
employed for 10 or more years and are either 65 and older, disabled
for 2 years or more, or have end-stage renal disease. Individuals are
eligible for Part B (pays for physician services) if they have Part
A, but must pay a monthly fee (around $50). Medicare does not pay for
medications, personal care services at home, or custodial nursing
home care, but does provide for skilled nursing facility
(rehabilitation or medical) in a nursing home for 100 days (per each
medical or rehabilitation incident separated by 60 days).
Molecular
genetics -
The study of how genes function to control cellular activies.
(Genetic engineering involves the application of knowledge about
molecular genetics in order to change living things by modifying
their DNA, so they will produce desired strains).
Motoneuron
(motor neuron) -
A nerve cell whose cell body is located in the brain and spinal cord
and whose axons leave the central nervous system by way of cranial
nerves or spinal roots. Motoneuron supply information to muscle. A
motor unit is the combination of the motoneuron and the set of muscle
fibers it innervates.
Motor- Referring
to nerves that give signals to muscles or glands in the body.
Motor
development -
The gradual acquisition of full control of all voluntary motor
movements common to the species.
MRI (Magnetic
Resonance Imaging) - A high-tech diagnostic tool to display tissues
unseen in X-rays or by other techniques.
Multiple
Sclerosis (MS) -
A chronic disease of the central nervous system where myelin, the
insulation on nerve fibers, is lost. MS is thought to be an
autoimmune dysfunction in which the body turns on itself for some
unknown reason.
Myelin -
A white, fatty insulating material for axons which produced in the
peripheral nervous system by Schwann cells, and in the central
nervous system by oligodendrocytes. Myelin is necessary for rapid
signal transmission along nerve fibers, ten to one hundred times
faster than in bare fibers lacking its insulation properties. It
insulates axons giving the "white matter" of the central
nervous system its characteristic color.
Myelogram -
A diagnostic test in which an opaque liquid is injected into the
spinal canal, producing an outline of it on X-rays or fluoroscope.
Myoclonus -
Involuntary, sharp, jerking muscular contractions, often painful.
Myotome -
The collection of muscle fibers innervated by the motor axons within
each segmental nerve (root).
Neurapraxia -
The first level of nerve injury. The large motor fibers are
predominately affected and anatomic continuity of the nerve is
preserved. The prognosis for recovery is excellent and usually
complete within a few days to weeks.
Nerve
Growth Factor (NGF) -
A "vitamin" for nerve cells. NGF, a protein, supports
survival of embryonic neurons, and regulates neurotransmitters.
Nerve
Impulse -
An electrical current is carried along the plasma membrane (outer
skin) nerve, and it may "start" in one of three ways: a)
spontaneous "ignition" of the nerve cell body, b) removal
of a suppressor impulse, and c) reception of an electrical impulse
from other nerve cells.
Neurogenic
Bladder -
Any bladder disturbance due to an injury of the nervous system.
Neurological
Level -
Refers to the lowest segment of the spinal cord with normal sensory
and motor function on both sides of the body. In fact, the segments
at which normal function is found often differ by side of body and in
terms of sensory vs. motor testing. Thus, up to four different
segments may be identified in determining the neurological level. In
cases such as this, generally each of these segments is separately
recorded and a single "level".
Neurolysis -
Destruction of peripheral nerves by radio frequency, heat, cutting or
by chemical injection. Used to treat spasticity.
Neuron -
A nerve cell that can receive and send information by way of synaptic
connections consisting of the cell body and extensions of the nerve
called axons and dendrites.
Neuropathic
/ Spinal Cord Pain -
Neuropathic (nerve-generated) pain is a problem experienced by SCI
patients. A sharp, almost electrical shock, type of pain will be felt
to the left of the injury and is the result of damage to the spine
and soft tissue surrounding the spine. Phantom limb pain or radiating
pain from the level of the lesion is related to the injury or
sysfunction at the nerve root or spinal cord.
Neurotmesis -
The most severe form of nerve injury. There is complete disruption
within the nerve and/or an actual severing of the nerve. This injury
needs surgical repair. There is wallerian degeneration of the nerve
distal to the site of the injury and the prognosis for recovery is
far poorer than in the case of neurapraxia or axonotmesis (the other
2 classes of nerve injuries). A nerve may not always have only one
type of injury. It is possible to have combined types of injuries
within a given nerve.
Neurotransmitter -
A chemical released from a neuron ending, at a synapse, to either
excite or inhibit the adjacent neuron or muscle cell. A chemical
synthesized within the nerve cell body, characteristic for this type
of nerve, and stored at the nerves in pods as granules. Release of
these chemicals into the synaptic cleft between axons facilitates
nerve transmissions.
Nucleic
acid -
Complex organic acids found in the nucleus of all living cells that
contain the genetic code essential to life.
Occupational
Therapist (OT) -
The member of the rehabilitation team who helps maximize a person's
independence.
Occupational
Therapy (OT) -
Structured activity focused on activities of daily living skills
(feeding, dressing, bathing, grooming), arm flexibility and
strengthening, neck control and posture, perceptual and cognitive
skills, and using adaptive equipment to facilitate ADL’s.
Oligodendrocyte -
A central nervous system glial cell. Oligodendrocytes are the site of
myelin manufacture for central nervous system neurons (the job of
Schwann cells in the peripheral nervous system).
Omentum -
Well-vascularized tissue of the gut.
Osteoporosis -
Loss of bone density, common in immobile bones after SCI.
Ostomy -
An opening in the skin to allow for a suprapubic cystostomy (catheter
drainage), for elimination of intestinal contents (colostomy or
ileostomy) or for passage of air (tracheostomy).
Papavarine -
A drug injected into the penis to produce an erection which acts by
increasing blood flow.
Paralytic
Ileus -
Loss of movement in the small intestine, resulting in gas and fluid
build-up. It usually lasts a few days after injury.
Paraplegia -
Refers to impairment of loss of motor and/or sensory function in the
thoracic, lumbar or sacral (but not cervical) segments of the spinal
cord, secondary to damage of neural elements within the spinal canal.
WIth paraplegia, arm functioning is spared, but, depending on the
level of injury, the trunk, legs, and pelvic organs may be involved.
There are some types of paralysis involving the legs that are
described by the impairment they cause (see Clinical Syndromes).
Paraplegic -
One who has loss of function below the cervical spinal cord segments,
wherein the upper body retains most function and sensation.
Paresis -
Weakness in voluntary muscle or slight paralysis.
Passive
Standing -
Standing on one's feet while being propped up in a standing frame or
other device. It is said to benefit bone strength.
Percussion -
Forceful tapping on congested parts of the chest to facilitate
postural drainage in persons with people with high-level tetraplegia.
Peripheral -Nerve
tissue not found in the brain or spinal cord.
Peripheral
Nervous System -
Nerves outside the spinal cord and brain (not part of the central
nervous system). If damaged, peripheral nerves have the ability to
regenerate.
Personal
Care Services -
Non-skilled assistance (bathing, dressing, light housework) provided
to individuals in their homes.
Phrenic
Nerve Stimulation -
Electrical stimulation of the nerve that fires the diaphragm muscle,
facilitating breathing in people with injury at the C1 or C2 level.
Physiatrist -
A doctor whose specialty is physical medicine and rehabilitation.
Physical
Therapist (PT) -
A key member of the rehabilitation team.
Physical
Therapy (PT) -
Structured activity focused on mobility skills (bed, transfers,
wheelchair use, walking), leg flexibility and strengthening, trunk
control and balance, endurance training, and using adaptive equipment
to facilitate mobility.
Piloerection -
"goose bumps"
Plasticity -
Long-term adaptive mechanism by which the nervous system restores or
modifies itself toward normal levels of function.
Posterior -
Back.
Postural
Drainage -
Using gravity to help the clear lungs of mucus by positioning the
head lower than chest.
Postural
Hypotension -
The reduction of blood pressure resulting in light-headedness.
Preservation -
The repetition of an idea or activity without an appropriate
stimulus.
Pressure
Release -
Relieving pressure from the ischial turberosities (bones on which we
sit) every 15 min. in order to prevent pressure sores.
Pressure
Sore -
Also known as decubitus ulcer. A potentially dangerous skin breakdown
due to pressure on skin resulting in infection, tissue death.
Priapism -
A dangerous condition where the penis remains erect due to retention
of blood.
Prone -
Lying on stomach.
Proprioception -
The sense of movement and position.
Prosthesis -
Replacement device for a body part, for example an artificial limb.
PVR
(Post Void Residual) -
The volume left in bladder after the patient voids (urinates).
Quad -
Generally, a high quad is someone with an injury at C1, C2, and C3.
some doctors also group c4 quads into this category. Mid-level quads
are those injured at C5. Low-level quads are those injured at C6 &
C7. This isn't written in stone, and some doctors consider C4, C5,
and C6 all as mid-level, with C7 being low-level.
Quad
Cough -
A method of helping a patient with tetraplegia cough by applying
external pressure to diaphragm, thus increasing the force and
clearing the respiratory tract.
Quadriparesis -
Partial loss of function all four (4) extremities of the body.
Quadriplegia -
Loss of function of any injured or diseased cervical spinal cord
segment, affecting all four body limbs. Outside the U.S. the term
tetraplegia is used (which is etymologically more accurate, combining
tetra + plegia, both from the Greek, rather than quadri + plegia, a
Latin/Greek amalgam).
Range
of Motion (ROM) -
The normal range of movement of any body joint. Range of Motion also
refers to exercises designed to maintain this range and prevent
contractures.
Receptor
(afferent) neuron -
The input nerve component of the reflex arc which conducts stimuli
from the environment toward the CNS.
Reciprocating
Gait Orthosis (RGO) -
A type of long-leg brace used for ambulation by paralyzed people.
Uses cables across the back to transfer energy from leg to leg,
thereby simulating a more natural gait.
Reflex -
An involuntary response to a stimulus involving nerves not under
control of the brain.
Reflex
arc -
In its simplest form, three components. Receptor, association, and
effector (efferent) neurons facilitate one-way transmission of nerve
impulses in a repetitive manner.
Reflux -
The backflow of urine from the bladder into the ureters and kidney.
Regeneration -
The regrowth of a cell or nerve fiber.
Rehabilitation -
Retraining to normal functionality or training for new functionality.
Residual
Urine -
Urine that remains in the bladder after voiding. Too much left can
lead to a bladder infection.
Restorative
Nursing (NRS) -
Replication of activities initiated by PT, OT, and SLP performed by
nursing staff (range of motion, dressing, hygiene, walking, feeding).
Retrograde
Pyelogram (RP) -
Insertion of contrast material directly into the kidney through an
instrument.
Rhizotomy -
The cutting, or interruption, of spinal nerve roots.
Sacral -
The fused vertebrae and spinal cord below the lumbar level.
Schwann
Cells -
Responsible in the peripheral nervous system for myelinating axons
they also provide trophic support in injury situation.
Secondary
Injury -
The biochemical and physiological changes that occur in the injured
spinal cord after the initial trauma has done its damage.
Self-Catheterization -
Intermittent catheterization, the goal of which is to empty the
bladder as needed, on one's own, minimizing risk of infection.
Sensory
Level and Motor Level -
When the term "sensory level" is used, it refers to the
lowest segment of the spinal cord with normal sensory function on
both sides of the body; the motor level is similarly defined with
respect to motor function. These "levels" are determined by
neurological examination of (1) a key sensory point with in each of
28 dermatomes on the right and 28 dermatomes on the left side of the
body, and (2) a key muscle within each of 10 myotomes on the right
and 10 myotomes on the left side of the body.
Shunt -
A tube used to drain a cavity. In the spinal cord, a shunt is used to
treat a syrinx by equalizing pressures between the syrinx and the
spinal fluids. In spinal bifida, it is used to reduce pressure of
hydrocephalus.
Skin
Breakdown -
Skin breakdowns (also termed "decubitus ulcers") occurs as
a result of excessive pressure, primarily over the bones of the
buttock.
Social
Work (SW) -
Supportive service for psychosocial adjustment and intervention,
financial resources, and discharge planning.
Space
Boots -
Plastic boots with foam linens worn on the feet when lying on your
side.
Spasticity -
Hyperactive muscles that move or jerk involuntarily. There are some
benefits to spasticity:
- Warning mechanism to identify pain or problems in areas of no sensation.
- Helps in spotting an oncoming urinary tract infection.
- Helps to maintain muscle size and bone strength.
- Helps to maintain circulation.
- Helps to prevent osteoporosis.
Speech
and Language Pathology (SLP) -
Structured activity focused on communication skills, perceptual and
cognitive skills, and swallowing.
Sphincterotomy -
The cutting of the bladder sphincter muscle to eliminate spasticity
and related voiding problems.
Spinal
accessory nerve -
Cranial Nerve XI. Largely motor, this nerve supplies sternomastoid
and trapezius muscles.
Spinal
nerves -
Sensory and motor nerves which connect the spinal cord to the
periphery of the body.
Spinal
Shock -
Similar to a concussion in the brain, spinal shock causes the system
shuts down.
Subluxation -
Complete or partial dislocation (as in shoulder).
Suctioning -
Removal of mucus and secretions from lungs. It is important for
people with high-level tetraplegia who lack ability to cough.
Suprapubic
Catheter -
A catheter surgically inserted into the bladder by incision above the
pubis.
Suprapubic
Cystostomy -
A small opening made in the bladder and through the abdomen,
sometimes to remove large stones, more commonly to establish a
catheter urinary drain.
Synapse -
The specialized junction between a neuron and another neuron or
muscle cell for transfer of information such as brain signals,
sensory inputs, etc., along the nervous system. These are the
junctions between the "sending" fibers of one nerve cell,
to the "receiving" fibers of other nerve cells. The axon
(sending fiber) ends in multiple branches, each of which has a
button-like enlargement that nearly touches the "receiving"
fibers of the other nerve cell bodies. Nerve cells "talk"
to each other via synapses. Basically the connection between the end
of a nerve and the adjacent structure, such as a muscle cell or
another nerve ending. Various transmitter chemicals liberated into
the synapse make nerve transmissions possible.
Syringomyelia -
The formation of a fluid-filled cavity (a syrinx) in an injured area
of the spinal cord, which is a result of nerve fiber degradation and
necrosis. It sometimes extends upward, extending also the
neurological deficit. Treatment often includes surgery to insert a
shunt for drainage of the cavity.
Syringomyelocele -
A congenital neural tube defect which can cause spinal bifida in
which spinal fluid fills a sac of spinal membrane.
Syrinx -
A cyst; a cavity.
Tendon
Lengthening -
A procedure, usually involving the Achilles tendon, to treat
contractures caused by spasms.
Tenodesis
(Hand Splint) -
Metal or plastic support for hand, wrist and/or fingers. Used to
facilitate grater function to a disabled hand by transferring wrist
extension into grip and finger control.
Tetraplegia -
(Quadriplegia) Refers to impairment or loss of motor and/or
sensory function in the cervical segments of the spinal cord due to
damage of neural elements within the spinal canal. Tetraplegia
results in impairment of function in the arms as well as in the
trunk, legs, and pelvic organs. It does not include brachial plexus
lesions or injury to peripheral nerves outside the neural canal.
Thoracic -
Pertaining to the chest, vertebrae or spinal cord segments between
the cervical and lumbar areas.
Thrombophlebitis -
A clot in a vein due to diminished blood flow which can occur in a
paralyzed leg. Symptoms include swelling and redness.
Tilt
Table -
A table which is used to gradually increase patients tolerance to
being in a standing position. Also used to teach partial weight
bearing and to give prolonged stretch in each position.
Tracheostomy -
Opening in windpipe to facilitate breathing.
Upper
Motor Neurons -
Long nerve cells that originate in the brain and travel in tracts
through the spinal cord. Any injury to these nerves cuts off contact
with brain control. Reflex activity is still intact, however
resulting in spasticity. For men with upper motor neuron injuries,
reflex erections are possible.
Urinary
Tract Infection (UTI) -
Bacterial invasion of the urinary tract, which includes bladder,
bladder neck and urethra. Symptoms of UTI include urine that is
cloudy, contains sediment and smells foul, and fever. UTI involving
the kidneys is preventable but dangerous. Medications often
prescribed for UTI include Keflex, Macrodantin, Furadantin, Septra,
Bactim, Mandelamine, penicillin, and amoxicillin. Side effects vary,
and may include nausea and vomiting, skin rash or hives.
Ventilator -
Mechanical device to facilitate breathing in persons with impaired
diaphragm function.
Vertebrae -
The bones that make up the spinal column.
Vital
Capacity -
The measure of air in a full breath. It is an important consideration
for people with high-level tetraplegia who also have impaired
pulmonary function.
Vital
Signs -
Consist of taking blood pressure, pulse, respiration and temperature.
Weaning -
Gradual removal of mechanical ventilation, as patient's lung strength
and vital capacity increases.
Zone
of Partial Preservation -
Refers to those dermatomes and myotomes below the neurological level
that remain partially innervated. When some impaired sensory and/or
motor function is found below the lowest normal segment, the exact
number of segments so affected make up the ZPP. The term is used only
with incomplete injuries.
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